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Seminars in Nuclear Medicine
Volume 31, Issue 4
, Pages 278-285
, October 2001
Newer methods of labeling diagnostic agents with Tc-99m
References
- . Technetium radiopharmaceuticals: Fundamentals, synthesis, structure, and development. Angew Chem Int Ed Engl. 1994;33:2258–2267
- . Potential technetium small molecule radiopharmaceuticals. Chem Rev. 1999;99:2205–2218
- . Technetium-99m-labeled receptorspecific small-molecule radiopharmaceuticals: Recent developments and encouraging results. Nucl Med Biol. 1997;24:485–498
- . 99mTc labeling of highly potent small peptides. Bioconjug Chem. 1997;8:621–636
- . 99mTc-labeled small peptides as diagnostic radiopharmaceuticals. Chem Rev. 1999;99:2235–2268
- . Small peptides radiolabeled with 99mTc. Q J Nucl Med. 1996;40:221–233
- Radiolabeling of monoclonal antibodies and fragments with technetium and rhenium. Bioconjug Chem. 1992;3:91–99
- . Progress in research on ligands, nuclides and techniques for labeling monoclonal antibodies. Int J Rad Appl Instrum B. 1991;18:589–603
- . Lipophilic Tc complexes. VI. Neutral oxotechnetium(V) complexes with monothiol/tridentate coordination. Inorg Chim Acta. 1989;165:163–166
- Stability versus reactivity of “3+1” mixed-ligand technetium-99m complexes in vitro and in vivo. Eur J Nucl Med. 1998;25:793–796
- TROTEC-1: A new high-affinity ligand for labeling of the dopamine transporter. J Med Chem. 1998;41:4429–4432
- Technetium(V) and rhenium(V) complexes for 5-HT2A serotonin receptor binding: Structureaffinity considerations. Nucl Med Biol. 1996;23:429–438
- Structural modification of receptor-binding technetium-99m complexes in order to improve brain uptake. Eur J Nucl Med. 1997;24:316–319
- Radiochemical synthesis and tissue distribution of Tc-99m-labeled 7alpha-substituted estradiol complexes. Nucl Med Biol. 2000;27:269–278
- . Synthesis and binding affinities of novel Re-containing 7a-substituted estradiol complexes: Models for breast cancer imaging agents. J Org Chem. 1999;64:8108–8121
- Synthesis and binding affinities of new 17 alpha-substituted estradiol-rhenium “n + 1” mixed-ligand and thioether-carbonyl complexes. Steroids. 1998;63:665–671
- Synthesis of novel progestin-rhenium conjugates as potential ligands for the progesterone receptor. Bioorg Med Chem. 1999;7:1827–1835
- Assessment of the in vitro and in vivo properties of a 99mTc-labeled inhibitor of the multidrug resistant gene product P-glycoprotein. Nucl Med Biol. 2000;27:135–141
- A novel organometallic aqua complex of technetium for the labeling of biomolecules: Synthesis of [99mTc(OH2)3(CO)3]+ from from [99mTcO4]− in aqueous solution and its reaction with a bifunctional ligand. J Am Chem Soc. 1998;120:7987–7988
- First application of fac-[99mTc(OH2)3(CO)3]+ in bioorganometallic chemistry: Design, structure, and in vitro affinity of a 5-HT1A receptor ligand labeled with 99MTc. J Am Chem Soc. 1999;121:6076–6077
- Influence of the denticity of ligand systems on the in vitro and in vivo behavior of (99m)Tc(I)-tricarbonyl complexes: A hint for the future functionalization of biomolecules. Bioconjug Chem. 2000;11:345–351
- In vitro and in vivo evaluation of bidentate, water-soluble phosphine ligands as anchor groups for the organometallic fac-[99mTc(CO)3]+-core. Nucl Med Biol. 1999;26:711–716
- Chemical and biological characterization of technetium(I) and rhenium(I) tricarbonyl complexes with dithioether ligands serving as linkers for coupling the Tc(CO)3 and Re(CO)3 moieties to biologically active molecules. Bioconjug Chem. 2000;11:414–424
- (abstr) Preparation and biological evaluation of 99mTc(I)-carbonyl labeled octreotate conjugates. J Nucl Med. 2000;41:156P
- Steps towards [(C5-Me5)TcO3] novel synthesis of [C5Me5)Tc(CO)3] from [{Tc(m3-OH)(CO)3}4] and oxidation of [(C5Me5)M(CO)3] (M = Tc, Re) with Br2. Polyhedron. 1998;17:1133–1140
- . The functional expression of antibody Fv fragments in Escherichia coli: Improved vectors and a generally applicable purification technique. Biotechnology (N Y). 1991;9:273–278
- Stable one-step technetium-99m labeling of His-tagged recombinant proteins with a novel Tc(I)-carbonyl complex. Nat Biotechnol. 1999;17:897–901
- . Boronic acids in the three-component synthesis of carbon-substituted cyclopentadienyl tricarbonyl rhenium complexes. J Am Chem Soc. 1998;120:13264–13265
- . A convenient three-component synthesis of substituted cyclopentadienyl tricarbonyl rhenium complexes. J Am Chem Soc. 1998;120:4514–4515
- . Three-component synthesis of substituted h5-cyclopentadienyl tricarbonylrhenium complexes: Scope, limitations, and mechanistic interpretations. Organometallics. 1998;18:2519–2530
- Synthesis and biological evaluation of Tc-99m-cyclopentadienyltricar-bonyltechnetiumlabeled octreotide. Nucl Med Biol. 1999;26:1–7
- . Preparation of cyclopentadienyl tricarbonylrhenium complexes using a double ligand transfer reaction. Organometallics. 1998;17:2009–2017
- . Protein and peptide labeling with (cyclopentadienyl)tricarbonyl rhenium and technetium. Bioconjug Chem. 1998;9:765–772
- Homodimeric and heterodimeric bis(amino thiol) oxometal complexes with rhenium(V) and technetium(V). Control of heterodimeric complex formation and an approach to metal complexes that mimic steroid hormones. J Med Chem. 1994;37:928–937
- . Selective formation of heterodimeric bis-bidentate aminothiol oxometal complexes of rhenium(V). J Am Chem Soc. 1993;115:7045–7046
- . Heterodimeric bis(amino thiol) complexes of oxorhenium(V) that mimic the structure of steroid hormones. Synthesis and stereochemical issues. J Org Chem. 1996;61:2624–2631
- . Synthesis of a tetradentate oxorhenium(V) complex mimic of a steroidal estrogen. J Org Chem. 1997;62:6290–6297
- Pharmacokinetics and renal handling of 99mTc-labeled peptides. J Nucl Med. 2000;41:177–182
- Technetium-99m-human polyclonal IgG radiolabeled via the hydrazino nicotinamide derivative for imaging focal sites of infection in rats. J Nucl Med. 1990;31:2022–2028
- Labeling a hydrazino nicotinamide-modified cyclic IIb/IIIa receptor antagonist with 99mTc using aminocarboxylates as coligands. Bioconjug Chem. 1996;7:63–71
- New and versatile ternary ligand system for technetium radiopharmaceuticals: Water soluble phosphines and tricine as coligands in labeling a hydrazinonicotinamidemodified cyclic glycoprotein IIb/IIIa receptor antagonist with 99mTc. Bioconjug Chem. 1997;8:146–154
- 99mTc-labeling of hydrazones of a hydrazinonicotinamide conjugated cyclic peptide. Bioconjug Chem. 1999;10:803–807
- . A novel ternary ligand system for 99mTc-labeling of hydrazino nicotinamide-modified biologically active molecules using imine-N-containing heterocycles as coligands. Bioconjug Chem. 1998;9:583–595
- RP463: A stabilized technetium-99m complex of a hydrazino nicotinamide derivatized chemotactic peptide for infection imaging. Bioconjug Chem. 1999;10:884–891
- . 99m-Technetium-labelled peptide-HYNIC conjugates: Effects of lipophilicity and stability on biodistribution. Nucl Med Biol. 1999;26:389–396
- Synthesis of stable hydrazones of a hydrazinonicotinyl-modified peptide for the preparation of 99mTc-labeled radiopharmaceuticals. Bioconjug Chem. 1999;10:808–814
- Development and biologic evaluation of a kit for preformed chelate technetium-99m radiolabeling of an antibody Fab fragment using a diamide dimercaptide chelating agent. J Nucl Med. 1991;32:1445–1451
- Radioimmunoscintigraphy in patients with early stage cutaneous malignant melanoma. J Nucl Med. 1996;37:252–257
- Detection and staging of small cell lung carcinoma with a technetium-labeled monoclonal antibody. A comparison with standard staging methods. Clin Nucl Med. 1992;17:439–445
- Simplified preformed chelate protein radiolabeling with technetium-99m mercaptoacetamidoadipoylglycylglycine (N3S-adipate). Bioconjug Chem. 1998;9:108–117
- Labeling cyclic glycoprotein IIb/IIIa receptor antagonists with 99mTc by the preformed chelate approach: Effects of chelators on properties of [99mTc]chelator-peptide conjugates. Bioconjug Chem. 1996;7:196–202
- 99mTc-labeling and in vivo studies of a bombesin analogue with a novel water-soluble dithiadiphosphine-based bifunctional chelating agent. Bioconjug Chem. 1999;10:254–260
- High-affinity no-carrieradded 99mTc-labeled chemotactic peptides for studies of inflammation in vivo. Bioconjug Chem. 1998;9:208–217
- . Validation and application of a solid phase chemistry method for preparation of high effective specific-activity technetium-99m radiopharmaceuticals. Nucl Med Biol. 1997;24:499–505
- Convenient preparation of no-carrier-added technetium-99m radiopharmaceuticals using solid-phase technology. Bioconjug Chem. 1999;10:832–837
- A convenient method of preparing high specific-activity technetium complexes using thiolcontaining chelators adsorbed on gold. J Am Chem Soc. 1999;121:11593–11594
- . Production of high purity 94mTc for positron emission tomography studies. Nucl Med Biol. 2000;27:323–328
- Technetium 94m-labeled methoxyisobutyl isonitrile: Dosimetry and resting cardiac imaging with positron emission tomography. J Nucl Cardiol. 1994;1:425–433
- Technetium-94m-teboroxime: Synthesis, dosimetry and initial PET imaging studies. J Nucl Med. 1993;34:1058–1066
- (abstr) Comparison of [94mTc]- and [99mTc]trodat-I as imaging agents for the dopamine transporter. J Labelled Compd Radiopharm. 1999;42:S45–S47
- Radiolabeling of an anti-carcinoembryonic antigen antibody Fab' fragment (CEA-Scan) with the positron-emitting radionuclide Tc-94m. Clin Cancer Res. 1999;5:3001s–3003s
PII: S0001-2998(01)80007-6
doi: 10.1053/snuc.2001.26182
© 2001 Published by Elsevier Inc.
« Previous
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Seminars in Nuclear Medicine
Volume 31, Issue 4
, Pages 278-285
, October 2001
