Seminars in Nuclear Medicine
Volume 31, Issue 3 , Pages 253-254 , July 2001

Diffuse liver and spleen accumulation on Tc-99m methylene diphosphonate bone scan

  • Shung-Shung Sun

      Affiliations

    • Department of Nuclear Medicine, China Medical College Hospital, Taichung
    • Division of Rheumatology-Immunology, China Medical College Hospital, Taichung
    • Department of Nuclear Medicine, Show-Chwan Memorial Hospital, Chunghua, Taiwan
    • Department of Nuclear Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
    • ,
  • Shih-Chuan Tsai

      Affiliations

    • Department of Nuclear Medicine, China Medical College Hospital, Taichung
    • Division of Rheumatology-Immunology, China Medical College Hospital, Taichung
    • Department of Nuclear Medicine, Show-Chwan Memorial Hospital, Chunghua, Taiwan
    • Department of Nuclear Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
    • ,
  • Che-Chun Su

      Affiliations

    • Department of Nuclear Medicine, China Medical College Hospital, Taichung
    • Division of Rheumatology-Immunology, China Medical College Hospital, Taichung
    • Department of Nuclear Medicine, Show-Chwan Memorial Hospital, Chunghua, Taiwan
    • Department of Nuclear Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
    • ,
  • Chia-Hung Kao

      Affiliations

    • Department of Nuclear Medicine, China Medical College Hospital, Taichung
    • Division of Rheumatology-Immunology, China Medical College Hospital, Taichung
    • Department of Nuclear Medicine, Show-Chwan Memorial Hospital, Chunghua, Taiwan
    • Department of Nuclear Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
    • Corresponding Author InformationAddress reprint requests to Chia-Hung Kao, MD, Department of Nuclear Medicine, Taichung Veterans General Hospital, 160 Taichung Harbor Road, Section 3, Taichung, 40705, Taiwan.

References 

  1. Hansen S, Stadalnik RC. Liver uptake of Tc-99m pyrophosphate. In: Semin Nucl Med. 12:1982;p. 89–91
  2. Poulose KP, Reba RC, Eckelman WC, et al. Extraosseous localization of Tc-99m-Sn pyrophosphate. Br J Radiol. 1975;48:724–726
  3. Guiberteau MI, Postsaid MS, McKusick KA. Accumulation of 99mTc diphosphonate in four patients with hepatic neoplasm: Case report. J Nuc Med. 1976;17:1060–1061
  4. Valdez VA, Jacobstein JG. Visualization of the liver with Tc-99m-EHDP in thalassemia major. Gastrointest Radiol. 1981;6:175–176
  5. Howman-Giles RB, Gilday DL, Ash JM, et al. Splenic accumulation of Tc-99m diphosphonate in thalassemia major. J Nucl Med. 1978;19:976–977
  6. Costello P, Gramm HF, Steinberg D. Simultaneous occurrence of functional asplenia and splenic accumulation of diphosphonate in metastatic breast carcinoma. J Nucl Med. 1977;18:1237–1238
  7. Baumert JE, Lantieri RL, Horning S, et al. Liver metastases of breast carcinoma detected on Tc-99m methylene diphosphonate bone scan. AJR Am J Roentgenol. 1980;134:389–391
  8. Oren VO, Uszler JM. Liver metastases of oat cell carcinoma of lung detected on 99mTc-diphosphonate bone scan. Clin Nucl Med. 1978;3:355–358
  9. Wilkinson RH, Gaedo JT. Concentration of Tc-99m methylene diphosphonate in hepatic metastases from squamous cell carcinoma. J Nucl Med. 1979;20:303–305
  10. Van Antwerp JD, O'Mara RE, Pitt MJ, et al. Technetium 99m-diphosphonate accumulation in amyloid. J Nucl Med. 1975;16:238–240

PII: S0001-2998(01)80025-8

doi: 10.1053/snuc.2001.24647

Seminars in Nuclear Medicine
Volume 31, Issue 3 , Pages 253-254 , July 2001

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