Seminars in Nuclear Medicine
Volume 33, Issue 4 , Pages 334-337 , October 2003

Gamut: soft tissue uptake of bone radiopharmaceuticals

  • Murat Tuncel

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Murat Tuncel, MD, Department of Nuclear Medicine, Hacettepe University, Medical School, 06,100 Sihhiye-Ankara, Turkey
    • Department of Nuclear Medicine, Hacettepe University, Medical School, Ankara, Turkey
  • ,
  • Belkis Erbas

      Affiliations

    • Department of Nuclear Medicine, Hacettepe University, Medical School, Ankara, Turkey
  • ,
  • Babak Mahmoudian

      Affiliations

    • Department of Nuclear Medicine, Hacettepe University, Medical School, Ankara, Turkey

References 

  1. Lim ST, Sohn MH. Unusual pattern of extraskeletal Tc-99m MDP uptake in traumatic crushing muscle injury. Clin Nucl Med. 2001;26:856–857
  2. Karanauskas S, Starshak RJ, Sty JR. Heterotopic Tc-99m MDP uptake secondary to phlebitis. Clin Nucl Med. 1991;16:329–331
  3. Tamgac F, Baillet G, Alper E, et al.  Extraskeletal accumulation of Tc-99m HMDP in a tuberculous cold abscess. Clin Nucl Med. 1995;20:1092
  4. Oguchi M, Higashi K, Taniguchi M, et al.  Calcified mediastinal metastases from ovarian cancer imaged with Tc-99m MDP SPECT. Clin Nucl Med. 1998;23:479–481
  5. Podrasky AE, Stark DD, Hattner RS, et al.  Radionuclide bone scanning in neuroblastoma (Skeletal metastases and primary tumor localization of 99mTc-MDP). AJR Am J Roentgenol. 1983;141:469–472
  6. Khayat G, Achram M, Rizk G. The role of breast scintigraphy in detecting breast masses. Br J Radiol. 1985;58:721–724
  7. Roman MR, Angelides S, Gibson MG. Unusually prolonged pooling of Tc-99m MDP in varicose veins. Clin Nucl Med. 2001;26:1034
  8. Petrocelli AR, Bassett LW, Mirra J, et al.  Scleroderma (Dystrophic calcification with spinal cord compression). J Rheumatol. 1988;15:1733–1735
  9. Itoh K, Baba Y, Taneichi K. Demonstration of systemic lymph nodes by bone scintigraphy in amyloidosis. Ann Nucl Med. 1992;6:95–97
  10. Okada J, Nomura M, Shirataka M, et al.  Prevalence of soft tissue calcifications in patients with SLE and effects of alfacarcidol. Lupus. 1999;8:456–461
  11. Veerapen K, Watt I, Dieppe P. Severe subcutaneous calcification in the ‘CREST’ syndrome (Evidence of high turnover of calcific deposits). Br J Rheumatol. 1987;26:89–92
  12. Ruiz Franco-Baux JV, Garcia Hernandez FJ, Correa Garcia M, et al.  Soft tissue visualization with 99m Tc-HDP in a case of dermatomyositis. Rev Esp Med Nucl. 1999;18:109
  13. Black AS, Kanat IO. A review of soft tissue calcifications. J Foot Surg. 1985;24:243–250
  14. Laroche M, Ricq G, Cantagrel A, et al.  Bone and joint involvement in adults with Werner’s syndrome. Rev Rhum Engl Ed. 1997;64:843–846
  15. Hung GU, Tsai SC, Kao CH, et al.  Incidental finding of pancreatic calcification on bone scan. Semin Nucl Med. 2000;30:231–233
  16. Walsh JS, Perniciaro C, Randle HW. Calcifying basal cell carcinomas. Dermatol Surg. 1999;25:49–51
  17. Alfonso I, Howard C, Lopez PF, et al.  Linear nevus sebaceous syndrome. A review. J Clin Neuroophthalmol. 1987;7:170–177
  18. Stemerman DH. The appearance of malignant fibrous histiocytoma on a three-phase bone scan. Clin Nucl Med. 1996;21:398–399
  19. Anghileri LJ. Soft tissue calcification induced by iron complexes. Calcif Tissue Int. 1992;51:83–84
  20. Basler RS, Watters JH, Taylor WB. Calcifying acne lesions. Int J Dermatol. 1977;16:755–758
  21. Martino G, Braccioni A, Cariati S, et al.  Pilomatrixoma or Malherbe’s calcifying epithelioma. A case report and review of the literature. G Chir. 2000;21:104–109
  22. Buka R, Wei H, Sapadin A, et al.  Pseudoxanthoma elasticum and calcinosis cutis. J Am Acad Dermatol. 2000;43:312–315
  23. Hwang GJ, Lee JD, Park CY, et al.  Reversible extraskeletal uptake of bone scanning in primary hyperparathyroidism. J Nucl Med. 1996;37:469–471
  24. Stokkel MP, Valdes Olmos RA, Hoefnagel CA, et al.  Tumor and therapy associated abnormal changes on bone scintigraphy. Old and new phenomena. Clin Nucl Med. 1993;18:821–828
  25. Campbell SB, Macfarlane DJ, Fleming SJ, et al.  Increased skeletal uptake of Tc-99m methylene diphosphonate in milk-alkali syndrome. Clin Nucl Med. 1994;19:207–211
  26. Gezici A, van Duijnhoven EM, Bakker SJ, et al.  Lung and gastric uptake in bone scintigraphy of sarcoidosis. J Nucl Med. 1996;37:1530–1532
  27. Braga FJ, Miranda JR, Lucca LJ, et al.  Heart and lung accumulation of Tc-99m MDP with normal radiographs in patients undergoing hemodialysis. Clin Nucl Med. 2000;25:377–378
  28. Matsuo T, Tsukamoto Y, Tamura M, et al.  Acute respiratory failure due to “pulmonary calciphylaxis” in a maintenance haemodialysis patient. Nephron. 2001;87:75–79
  29. Corstens F, Kerremans A, Claessens R. Resolution of massive technetium-99m methylene diphosphonate uptake in the stomach in vitamin D intoxication. J Nucl Med. 1986;27:219–222
  30. Ruiz-Genao DP, Rios-Buceta L, Herrero L, et al.  Massive scrotal calcinosis. Dermatol Surg. 2002;28:745–747
  31. Schepis C, Siragusa M, Palazzo R, et al.  Milia-like idiopathic calcinosis cutis (An unusual dermatosis associated with Down syndrome). Br J Dermatol. 1996;134:143–146
  32. Juzych LA, Nordby CA. Subepidermal calcified nodule. Pediatr Dermatol. 2001;18:238–240
  33. Peller PJ, Ho VB, Kransdorf MJ. Extraosseous Tc-99m MDP uptake (A pathophysiologic approach). Radiographics. 1993;13:715–734
  34. Mendoza LE, Lavery LA, Adam RC. Calcinosis cutis circumscripta. A literature review and case report. J Am Podiatr Med Assoc. 1990;80:97–99
  35. Cousins MA, Jones DB, Whyte MP, et al.  Surgical management of calcinosis cutis universalis in systemic lupus erythematosus. Arthritis Rheum. 1997;40:570–572
  36. Orellana P, Velasquez C, Meneses L, et al.  Tc-99m MDP uptake secondary to soft tissue extravasation of calcium gluconate in a newborn thought to have osteomyelitis. Clin Nucl Med. 2002;27:653–655
  37. Janigan DT, Perey B, Marrie TJ, et al.  Skin necrosis (An unusual complication of hyperphosphatemia during total parenteral nutrition therapy). JPEN J Parenter Enteral Nutr. 1997;21:50–52
  38. Fig LM, Shapiro B, Shulkin BL. Uptake of Tc-99m MDP in soft tissue calcific deposits due to the tumor lysis syndrome. Clin Nucl Med. 1988;13:765–767

PII: S0001-2998(03)00037-0

doi: 10.1016/S0001-2998(03)00037-0

Seminars in Nuclear Medicine
Volume 33, Issue 4 , Pages 334-337 , October 2003