Seminars in Nuclear Medicine
Volume 33, Issue 3 , Pages 193-204 , July 2003

PET/CT scanners: A hardware approach to image fusion

References 

  1. Weber WA, Avril N, Schwaiger M. Relevance of positron emission tomography PET in oncology. Strahlenther Onkol. 1999;175:356–373
  2. Pelizzari CA, Chen GTY, Spelbring DR, et al.  Accurate three-dimensional registration of CT, PET and MR images of the brain. J Comp Assist Tomogr. 1989;13:20–26
  3. Pietrzyk U, Herholtz K, Heiss W-D. Three-dimensional alignment of functional and morphological tomograms. J Comput Assist Tomogr. 1990;14:51–59
  4. Woods RP, Mazziotta JC, Cherry SR. MRI-PET registration with an automated algorithm. J Comp Assist Tomogr. 1993;17:536–546
  5. Wahl RL, Quint LE, Cieslak RD, et al.  “Anatometabolic” tumor imaging: Fusion of FDG PET with CT or MRI to localize foci of increased activity. J Nucl Med. 1993;34:1190–1197
  6. Beyer T, Townsend DW, Brun T, et al.  A combined PET/CT scanner for clinical oncology. J Nucl Med. 2000;41:1369–1379
  7. Charron M, Beyer T, Bohnen N, et al.  Image analysis in patients with cancer: Studies with a combined PET and CT scanner. Clin Nucl Med. 2000;25:905–910
  8. Kluetz PG, Meltzer CC, Villemagne MD, et al.  Combined PET/CT imaging in oncology: Impact on patient management. Clin Posit Imaging. 2001;3:1–8
  9. Meltzer CC, Martinelli MA, Beyer T, et al.  Whole-body FDG PET imaging in the abdomen: Value of combined PET/CT. J Nucl Med. 2001;42:35P; (abstr)
  10. Meltzer CC, Snyderman CH, Fukui MB, et al.  Combined FDG PET/CT imaging in head and neck cancer: Impact on patient management. J Nucl Med. 2001;42:36P; (abstr)
  11. Blodgett TM, Meltzer CC, Townsend DW, et al.  PET/CT in re-staging patients with ovarian cancer. J Nucl Med. 2002;45:310P; (abstr)
  12. Blodgett TM, Meltzer CC, Townsend DW, et al.  PET/CT in staging and re-staging patients with cervical cancer. J Nucl Med. 2002;45:310P; (abstr)
  13. Bar-Shalom R, Keidar Z, Guralnik L, et al.  Added value of fused PET/CT imaging with FDG in diagnostic imaging and management of cancer patients. J Nucl Med. 2002;43:32P; (abstr)
  14. Dizendorf E, Ciernik IF, Baumert B, et al.  Impact of integrated PET/CT scanning on external beam radiation treatment planning. J Nucl Med. 2002;43:33P; (abstr)
  15. Freudenberg LS, Antoch G, Mueller SP, et al.  Preliminary results of whole body FDG-PET/CT in lymphoma. J Nucl Med. 2002;43:30P; (abstr)
  16. Yeung HW, Schoder H, Larson SM. Utility of PET/CT for assessing equivocal PET lesions in oncology—Initial experience. J Nucl Med. 2002;43:32P; (abstr)
  17. Keidar Z, Bar-Shalom R, Guralnik L, et al.  Hybrid imaging using PET/CT with 18F-FDG in suspected recurrence of lung cancer. Diagnostic value and impact on patient management. J Nucl Med. 2002;43:32P; (abstr)
  18. Steinert HC, Hany TF, Kamel E, et al.  Impact of integrated PET/CT scanning on pre-operative staging of lung cancer. J Nucl Med. 2002;43:151P; (abstr)
  19. Osman MM, Cohade C, Leal J, et al.  Direct comparison of FDG-PET and PET-CT imaging in staging and re-staging patients with lung cancer. J Nucl Med. 2002;43:151P; (abstr)
  20. Hasegawa BH, Stebler B, Rutt BK, et al.  A prototype high-purity germanium detector system with fast photon-counting circuitry for medical imaging. Med Phys. 1991;18:900–909
  21. Lang TF, Hasegawa BH, Soo Chin L, et al.  Description of a prototype emission-transmission computed tomography imaging system. J Nucl Med. 1992;33:1881–1887
  22. Hasegawa BH, Lang TF, Brown EL, et al.  Object specific attenuation correction of SPECT with correlated dual-energy X-ray CT. IEEE Trans Nucl Sci NS. 1993;40:1242–1252
  23. Blankespoor SC, Xu X, Kaiki K, et al.  Attenuation correction of SPECT using X-ray CT on an emission-transmission CT system: myocardial perfusion assessment. IEEE Trans Nucl Sci. 1996;43:2263–2274
  24. Townsend DW, Beyer T, Kinahan PE, et al.  The SMART scanner: A combined PET/CT tomograph for clinical oncology. IEEE Nucl Sci Symp Conf Rec. 1998;M5–M11
  25. Townsend DW. A combined PET/CT scanner. The choices. J Nucl Med. 2001;3:533–534
  26. Bailey DL, Young H, Bloomfield PM, et al.  ECAT ART - a continuously rotating PET camera: Performance characteristics, initial clinical studies and installation considerations in a nuclear medicine department. Eur J Nuc Med. 1997;24:6–15
  27. Townsend DW, Beyer T, Kinahan PE, et al.  Recent studies with a combined PET/CT scanner: A synergistic approach to patient management. In: Proceedings of the International PET Symposium, Hokkaido, Japan.  Tamaki N,  Tsukamoto E editor. Positron Emission Tomography in the Millenium. 2000;p. 220–244
  28. Townsend DW, Cherry SR. Combining anatomy with function. The path to true image fusion. Eur Radiol. 2001;11:1968–1974
  29. Jaroff L. A winning combination. Time. 2000;156(23):72–74
  30. Comtat C, Kinahan PE, Defrise M, et al.  Fast reconstruction of 3D PET data with accurate statistical modeling. IEEE Trans Nucl Sci. 1998;45:1083–1089
  31. Patton JA, Delbeke D, Sandler MP. Image fusion using an integrated dual-head coincidence camera with x-ray tube-based attenuation maps. J Nucl Med. 2000;41:1364–1368
  32. Kinahan PE, Townsend DW, Beyer T, et al.  Attenuation correction for a combined 3D PET/CT scanner. Med Phys. 1998;25:2046–2053
  33. Osman MM, Cohade C, Nakamoto Y, et al.  Clinically significant inaccurate localization of lesions with PET/CT: Frequency in 300 patients. J Nucl Med. 2003;44:240–243
  34. Yau YY, Coel M, Chan WS, et al.  Application of IV contrast in PET-CT: Does it really produce attenuation correction error. J Nucl Med. 2003;44:272P; (abstr)
  35. Carney JP, Beyer T, Brasse D, et al.  Clinical PET/CT scanning using oral CT contrast agents. J Nucl Med. 2002;45:57P; (abstr)

 Address reprint requests to David W. Townsend, PhD, Department of Medicine, University of Tennessee, 1924 Alcoa Highway, Knoxville, TN 37920-6999.

☆☆ Supported by National Cancer Institute Grant CA 65856.

 0001-2998/03/3303-0005$30.00/0

PII: S0001-2998(03)70005-1

doi: 10.1053/snuc.2003.127314

Seminars in Nuclear Medicine
Volume 33, Issue 3 , Pages 193-204 , July 2003