Developments in instrumentation for emission computed tomography*
Article Outline
Instrumentation for emission computed tomography continues to evolve, taking advantage of developments in detector technology, data processing and correction methods, and reconstruction algorithms. This article reviews the basic principles and latest developments in emission computed tomography instrumentation, for both positron emission tomography and single-photon emission computed tomography applications.
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References
- Positron ranges obtained from biomedically important positron-emitting radionuclides. J Nucl Med. 1975;16:1174–1176
- Effect of positron range on spatial resolution. J Nucl Med. 1975;16:649–652
- . The physics of positron emission tomography. In: Bermann SR, Sobel BE editor. Positron Emission Tomography of the Heart. Mount Kisco, NY: Futura Publishing Inc; 1992;p. 13–44
- On the angular distribution of two-photon annihilation radiation. Phys Rev. 1950;77:205–212
- A new computerized tomographic imaging system for positron-emitting radiopharmaceuticals. J Nucl Med. 1978;19:635–647
- Design considerations for a positron emission tomography (PETT-V) for imaging of brain. J Comput Assist Tomogr. 1978;2:539–544
- Design of a high resolution positron emission tomograph: The Neuro-PET. J Comput Assist Tomogr. 1980;4:5–13
- . Performance evaluation of a positron tomograph designed for brain imaging. J Nucl Med. 1983;24:245–257
- A positron tomography with 600 BGO crystals and 2.6 mm resolution. IEEE Trans Nucl Sci. 1988;35:659–664
- . A multicrystal two dimensional BGO detector system for positron emission tomography. IEEE Trans Nucl Sci. 1986;33:460–463
- Performance characteristics of a whole-body PET scanner. J Nucl Med. 1994;35:1398–1406
- Investigation of the performance of the General Electric ADVANCE positron emission tomograph in 3D mode. IEEE Trans Nucl Sci. 1996;43:2199–2206
- Performance evaluation of the whole-body PET scanner ECAT EXACT HR+ following the IEC standard. IEEE Trans Nucl Sci. 1997;44:1172–1179
- An analog decoding BGO block detector using circular photomultipliers. IEEE Trans Nucl Sci. 1995;42:1095–1101
- . Gamma-ray and positron scintillation camera. Nucleonics. 1963;21:10–56
- . A positron camera using position-sensitive detectors: PENN-PET. J Nucl Med. 1986;27:90–98
- Continuous-slice PENN-PET: A positron tomograph with volume imaging capability. J Nucl Med. 1990;31:617–627
- Performance of a whole-body PET scanner using curve-plate NaI(T1) detectors. J Nucl Med. 2001;42:1821–1830
- . Shortening of detector signals in passive filters for pile-up reduction. Nucl Instr Methods. 1969;71:1–12
- Event localization in a continuous scintillation detector using digital processing. IEEE Trans Nucl Sci. 1986;33:550–555
- . A local coincidence triggering system for PET tomographs composed of large-area position-sensitive detectors. IEEE Trans Nucl Sci. 1990;37:730–736
- Positron tomograph employing a one dimension BGO scintillation camera. IEEE Trans Nucl Sci. 1983;30:661–664
- Cylindrical PET detector design. IEEE Trans Nucl Sci. 1988;35:675–679
- Performance measurements for the GSO-based brain PET camera (G-PET). In: IEEE Nuclear Science Symposium and Medical Imaging Conference Record. San Diego, CA. 2001;
- A comparison of PET detector modules employing rectangular and round photomultiplier tubes. IEEE Trans Nucl Sci. 1995;42:1064–1068
- Scintillation performance of large Ce-doped Cd2SiO5 (GSO) single crystal. In: IEEE Nuclear Science Symposium and Medical Imaging Conference Record. Albuquerque, NM. 1997;
- . Cerium-doped lutetium oxyorthosilicate: A fast, efficient new scintillator. IEEE Trans Nucl Sci. 1992;39:1161–1166
- . Inorganic scintillators in medical imaging. Phys Med Biol. 2002;47:R85–R106
- Energy resolution of scintillation detectors readout with large area avalanche photodiodes and photomultipliers. IEEE Trans Nucl Sci. 1998;45:472–477
- Performance characteristics of a dual head SPECT scanner with PET capability. In: IEEE Nuclear Science Symposium and Medical Imaging Conference Record. San Francisco, CA. 1995;
- Initial characterization of the Siemens E.CAM+: A dual detector camera with coincidence imaging capability. In: IEEE Nuclear Science Symposium and Medical Imaging Conference Record. Toronto, Canada. 1998;
- NEMA NU 2-2000+ performance measurements on an ADAC MCD camera. IEEE Trans Nucl Sci. 2001;48:1518–1523
- Performance evaluation of the positron scanner ECAT EXACT. J Comput Assist Tomogr. 1992;16:804–813
- Rotating positron tomographs revisited. Phys Med Biol. 1994;39:401–410
- Fully three-dimensional reconstruction for a PET camera with retractable septa. IEEE Trans Med Imag. 1991;10:505–512
- Physical performance of a positron tomograph for brain imaging with retractable septa. Phys Med Biol. 1992;37:1637–1655
- . List-mode likelihood. J Opt Soc Am A. 1997;14:2914–2923
- . Fast accurate iterative reconstruction for low-statistics positron volume imaging. Phys Med Biol. 1998;43:835–846
- A computer assisted ring detector positron camera system for reconstruction tomography of the brain. IEEE Trans Nucl Sci. 1978;25:624–637
- . Positron emission tomography imaging — Technical considerations. In: Semin Nucl Med. 16:1986;p. 35–50
- Quantitative potentials of dynamic emission computed tomography. J Nucl Med. 1978;19:309–315
- Exact and approximate rebinning algorithms for 3D PET data. IEEE Trans Med Imag. 1997;11:145–158
- . Assessment of image quality with a fast fully 3D reconstruction algorithm. In: IEEE Nuclear Science Symposium and Medical Imaging Conference Record. San Diego, CA. 2001;
- . Quantitation in positron emission computed tomography: 7. A technique to reduce noise in accidental coincidence measurements and coincidence efficiency calibration. J Comput Assist Tomogr. 1986;10:845–850
- Randoms variance reduction in 3D PET. Phys Med Biol. 1999;44:941–954
- The effect of activity outside the direct field of view in 3D-only whole-body positron tomograph. Phys Med Biol. 1998;43:895–904
- A study of external end-shields for PET. In: IEEE Nuclear Science Symposium and Medical Imaging Conference Record. Seattle, WA. 1999;
- . Evaluation of a neck shield for use during neurological studies with a whole-body PET scanner. IEEE Trans Nucl Sci. 2001;48:1512–1517
- Design of patient shielding to reduce the effects of out-of-field radioactivity in 3D PET. In: IEEE Nuclear Science Symposium and Medical Imaging Conference Record. Toronto, Canada. 1998;
- . A prototype axial shield for use in 3D whole-body PET. IEEE Trans Nucl Sci. 2001;48:10–15
- Correction for scattered radiation in a ring detector positron camera by integral transformation of the projections. J Comput Assist Tomogr. 1983;7:42–50
- Scatter correction in the transaxial slices of a whole-body positron emission tomograph. Phys Med Biol. 1993;38:717–728
- . A convolution-subtraction scatter correction method for 3D PET. Phys Med Biol. 1994;39:411–424
- . Model-based scatter correction for fully 3-D PET. Phys Med Biol. 1996;41:153–176
- Evaluation of simulationbased scatter correction for 3-D PET cardiac imaging. IEEE Trans Nucl Sci. 1997;44:90–97
- . Measuring PET scanner sensitivity: Relating count rates to image signal-to-noise ratios using noise equivalent counts. IEEE Trans Nucl Sci. 1990;37:783–788
- . The orbiting rod source: Improving performance in PET transmission correction scans. In: Esser P editors. Emission Computed Tomography—Current Trends. New York, NY: Society of Nuclear Medicine; 1983;
- . Postinjection transmission attenuation measurements for PET. IEEE Trans Nucl Sci. 1988;35:757–761
- (abstr) Validation of postinjection transmission measurements for PET. J Nucl Med. 1989;30:825
- Local threshold for segmented attenuation correction of PET imaging of the thorax. IEEE Trans Nucl Sci. 1994;41:1532–1537
- An automatic classification technique for attenuation correction in positron emission tomography. Eur J Nucl Med. 1999;26:447–458
- . Attenuation correction in PET using single photon transmission measurement. Med Phys. 1994;21:771–778
- Singles transmission scans performed post-injection for quantitative whole-body PET imaging. IEEE Trans Nucl Sci. 1997;44:1329–1335
- Singles transmission in volume imaging PET with a Cs-137 source. Phys Med Biol. 1995;40:929–944
- A combined PET/CT scanner for clinical oncology. J Nucl Med. 2000;41:1369–1379
- The ECAT HRRT: Performance and first clinical application of the new high resolution research tomograph. IEEE Trans Nucl Sci. 2002;49:104–110
- . Visualization of gamma-ray emitting isotopes in the human body. In: Proceedings of the International Conference on the Peaceful Uses of Atomic Energy. 1956;
- . A comparison of the uniformity requirements for SPECT image reconstruction using FBP and OSEM techniques. J Nucl Med Technol. 2001;29:79–83
- . Instrument- and computer-related problems and artifacts in nuclear medicine. In: Semin Nucl Med. 26:1996;p. 256–277
- Analysis and correction of spatial distortions produced by the gamma camera. J Nucl Med. 1972;13:307–312
- (editorial comment) . Analysis and correction of spatial distortions produced by the gamma camera. J Nucl Med. 1973;14:125–126
- . Field flood uniformity correction: Benefits or pitfalls?. J Nucl Med. 1976;17:653–656
- . A measure of Anger-camera linearity: Results with and without a corrector. J Nucl Med. 1981;22:1069–1074
- . Quantitative assessment of linearity of scintillation cameras. Radiology. 1980;136:790–792
- . A new development in single gamma transaxial tomography—Union Carbide focused collimator scanner. IEEE Trans Nucl Sci. 1979;26:2710–2712
- . New multi-dimensional reconstructions for the 12-detectors, scanned focal point, single-photon tomograph. Phys Med Biol. 1992;37:579–586
- (abstr) . Imaging characteristics of ASPECT, a singlecrystal ring camera for dedicated brain SPECT. J Nucl Med. 1989;30:796
- Quantitative analysis of seven-pinhole tomographic thallium-201 scintigrams: Improved sensitivity and estimation of the extent of coronary involvement by evaluation of radiotracer uptake and clearance. J Am Coll Cardiol. 1984;3:1178–1186
- Myocardial [18F]FDG tomography using a conventional gamma camera and a seven pinhole collimator. J Comput Assist Tomogr. 1994;18:102–109
- Quantitative analysis of acute myocardial infarct in rat hearts with ischemia-reperfusion using a high-resolution stationary SPECT system. J Nucl Med. 2002;43:933–939
- . A method for attenuation correction in radionuclide computed tomography. IEEE Trans Nucl Sci. 1978;25:638–643
- . Transmission scanning in emission tomography. Eur J Nucl Med. 1998;25:774–787
- . Performance parameters of a positron imaging camera. IEEE Trans Nucl Sci. 1976;23:528–537
- . The high count rate performance of a two-dimensionally position-sensitive detector for positron emission tomography. Phys Med Biol. 1989;34:437–456
- Feasibility of a high-speed gamma-camera design using the high-yield-pileup-event-recovery method. J Nucl Med. 2001;42:624–632
- . An electronically collimated gamma camera for single photon emission computed tomography. Part I: Theoretical considerations and design criteria. Med Phys. 1983;10:421–427
- . An electronically collimated gamma camera for single photon emission computed tomography. Part II: Image reconstruction and preliminary experimental measurements. Med Phys. 1983;10:428–435
- A data acquisition system for a ring Compton camera. In: IEEE Nuclear Science Symposium and Medical Imaging Conference Record. Lyon, France. 2000;
- Influence of the detector parameters on a Compton camera. In: IEEE Nuclear Science Symposium and Medical Imaging Conference Record. Lyon, France. 2000;
- Silicon detector for a Compton camera in nuclear medical imaging. In: IEEE Nuclear Science Symposium and Medical Imaging Conference Record. Lyon, France. 2000;
- A Compton camera for multitracer imaging. IEEE Trans Nucl Sci. 2001;48:656–661
- Improved modeling of system response in list mode EM reconstruction of Compton scatter camera images. IEEE Trans Nucl Sci. 2001;48:111–116
- . In: Design and Optimization of a Compton Camera for Nuclear Medicine Applications. New Haven, CT: Department of Applied Physics, Yale University; 2001;
* Supported by Department of Energy Grant DE-FG02-88ER60642 (M.E.D.-W., J.S.K.).
PII: S0001-2998(03)80004-1
doi:10.1053/snuc.2003.127295
© 2003 Published by Elsevier Inc.
