Seminars in Nuclear Medicine
Volume 34, Issue 2 , Pages 159-163 , April 2004

Pulmonary hypertrophic osteoarthropathy and its resolution

  • Wei-Jen Shih

      Affiliations

    • Nuclear Medicine Service, Lexington VA Medical Center, Lexington, KY, USA
    • Department of Diagnostic Radiology, College of Medicine, University of Kentucky Medical Center, Lexington, KY, USA
    • Corresponding Author InformationAddress reprint requests to Wei-Jen Shih, MD, Nuclear Medicine Service, Lexington VA Medical Center, 1101 Veterans Drive, Lexington, KY 40502-2236, USA

References 

  1. Bradford R, Griffiths MH, Goldstraw P. Hypertrophic pulmonary osteoarthropathy, in association with a bronchial carcinoid tumor. Br J Dis Chest. 1983;78:278–281
  2. Steiner H, Dahlback OV, Waldenstrom J. Ecotpic growth hormone production and osteoarthropathy in carcinoma of the bronchus. Lancet. 1968;1:783–785
  3. Normori H, Kobayashi R, Kubo A. Lung cancer containing growth hormone-releasing hormone associated with hyupertrophic osteoarthropathy. Case report. Scand J Thorac Cardiovasc Surg. 1994;28:149–152
  4. Uchisako H, Suga K, Tanaka N, et al.  Bone scintigraphy in growth hormone-secreting pulmonary cancer and hypertrophic osteoarthropathy. J Nucl Med. 1995;36:822–829 8–7
  5. Johnson SA, Spiller PA, Faull CM. Treatment of resistant pain in hyperrophic pulmonary osteoarthropathy with subcutaneous octreotide. Thorax. 1997;52:289–299
  6. Morgan B, Coakley F, Finlay D, et al.  Hypertrophic osteoarthropathy in staging skeletal scintigraphy of lung cancer. Clin Radiol. 1996;51:694–697
  7. Pineda C, Fonseca C, Martinez-Lavin M. The spectrum of soft tissue and skeletal abnormalities of hypertrophic osteoarthropathy. J Rheumatol. 1990;17:626–632
  8. Ginsburg J. Clubbing of the fingers. In:  Hamilton WS,  Down P editor. Handbook of Physiology. Physiology, Section 2: Circulation. vol III:Washington, DC: American Physiological Society; 1965;p. 2377–2388
  9. Hansoti RC, Sharma S. Cirrhosis of the liver simulating congenital cyanotic heart disease. Chest. 1989;96:843–848
  10. Dickinson CJ. The etiology of clubbing and hypertrophic osteoarthropathy. Eur J Clin Invest. 1993;23:330–338
  11. Golder W, Wolf KJ. CT-guided aspiration biopsy of infected aortic-graft in a patient with hypertrophic osteoarthropathy. Acta Radiologica. 2001;42:59–62
  12. Ho A, Williams DM, Zelenock GB, et al.  Unilateral hypertrophic osteoarhropathy in a patient with an infected axillary-axillary by pass graft. Radilogy. 1987;162:573–574
  13. Walter RD, Resnick D. Hypertrophic osteoarthropath ofa lower extremity in association with arterial graft sepsis. AJR. 1981;137:1059–1061
  14. Witte LD, Kaplan KL, Nossel HL, et al.  Studies of the release from human platelets of the growth factor for human arterial smooth muscle cells. Circ Res. 1978;42:402–409
  15. Silveira LH, Martinez-Lavin M, Pineda C, et al.  Vascular endothelial growth factor and hypertrophic osteoarthropathy. Clin Exp Rheumatol. 2000;18:57–62
  16. Mito K, Maruyama R, Uenishi Y, et al.  Hypertrophic pulmonary osteoarthropathy associated with non-small cell lung cancer demonstrated growth hormone-releasing hormone by immunohistochemical analysis. Intern Med. 2002;40:532–535
  17. Gosney MA, Gosney JR, Lye M. Plasma growth hormone and digital clubbing in carcinoma of the bronchus. Thorax. 1990;45:545–547
  18. Penson RT, Rudd RM. Commentary (octrotide and hypertrophic pulmonary osteoarthropathy). Thorax. 1997;52:297–298
  19. Hung GU, Kao CH, Lin WY, et al.  Rapid resolution of hypertrophic pulmonary osteoarthropathy after resection of a lung mass caused by xanthogranulomatous inflammation. Clin Nucl Med. 2000;25:1029–1030
  20. Campeau RJ, Rosales OR, Gracia OM, et al.  Resolution of hypertrophic osteoarthropathy after radiotherapy in the absence of tumor response. Clin Nucl Med. 1989;6:453–455
  21. Rao G, Guruprakash GH, Poulose KP, et al.  Improvement in hypertrophic pulmonary osteoarthropathy after radiotherapy to metastasis. AJR. 1979;133:944–946
  22. Dalgleish AG. Hypertrophic osteoarthropathy (response to chemotherapy without documented tumor response). Aust N Z J Med. 1983;13:513–516
  23. Vaquer R, Dunn EK, Bhat S, et al.  Reversible pulmonary uptake and hypertrophic pulmonary osteoarthropathic distribution of Tc-99m MDP in a case of Pneumocystis carinii penurmnia. J Nucl Med. 1989;30:1563–1567
  24. Vasudevan CP, Suppiah P, Udoshi MB, et al.  Reversible autonomic neuropathy and hypertrophic osteoarthropathy in a patient with bronchogenic carcinoma. Chest. 1981;79:479–481
  25. Kebudi R, Ayan I, Erseven G, et al.  Hypertrophic Osteoarthropathy and intrathoracic osteoarthropathy Hodgkin diseased of childhood. Med Pediatr Oncol. 1997;29:578–581
  26. Horak E, Olinsky A, Chow CW, et al.  Multiple cavitating pulmonary nodules and clubbing in a 12-year-old Girl. Pedair Pulmonol. 2002;34:147–149
  27. McLigeyo SO, Mbui J, Kungu A, et al.  Fibrosarcoma of the lung with extrapulmonary manifestation (case report). East Arf Med J. 1995;72:465–467
  28. Meade P, Moad J, Fellows D, et al.  Carcinosarcoma of the lung with hypertrophic pulmonary osteoarthropathy. Ann Thorac Surg. 1991;51:488–490
  29. Davis RA, Darby M, Richards MA. Hypertrophic pulmonary osteoarthopathy in pulmonary metastatic disease. A case report and review of the literature. Clin Radiol. 1991;43:268–271
  30. Matthay MA, Matthay RA, Mills DM, et al.  Hypertrophic osteoarthropathy in adults with cystic fibrosis. Thorax. 1976;31:572–575
  31. Athreya BH, Borns P, Rosenlung ML. Cystic fibrosis and hypertrophic osteoarthropathy in children. Report of three cases. Am J Dis Child. 1975;129:634–637
  32. Alloway JA, Nashel DJ, Rohatgi PK. Sarcoidosis and hypertrophic osteoarthropathy. J Rheumatol. 1992;19:180–181
  33. Hogosson C, Bahabri S, Rifai A, et al.  Hypertrophic osteoarthropathy caused by lipid pneumonia. Pediatr Radio. 1995;25:482–483
  34. Mas-Estelles F, Andres V, Muro D, et al.  Plasma cell granuloma of the lung in childhood (atypical radiologic findings and association with hypertrophic osteoarthropathy). Pedatr Radiol. 1995;25:369–372
  35. Beluff G, Marseglia GL, Monafo V, et al.  Pulmonary hypertrophic osteoarthropathy in a child with late-onset agammablobulinemia. Eur J Pediatr. 1982;139:199–201
  36. Engels LG, Boerbooms AM, Van Herwaarden DL. Neth J Med. 1980;23:117–119
  37. Emri S, Coplu L, Selcuk ZT, et al.  Hypertrophic pulmonary alveolar microlithiasis in a patient with pulmonary alveolar microlithiasis. Thorax. 1991;46:145–146
  38. Biswal BM, Ahmed NM. Hypertrophic osteoartheropathy (An unusual manifestation in nasopharyngeal cancer). Austr Radiol. 2001;45:71–73
  39. Varan A, Kutluk T, Demirkazik FB, et al.  Hypertrophic osteoarthropathy in a child with nasopharygeal carcinoma. Pediatr Radiol. 2000;30:570–572
  40. Rothschild BM, Sebes JI. Hypertrophic osteoarthropathy associated with carcinoma of the esophagus (Report of a case lacking pleuropulmonary involvement and review of the literature). Am J Gastroenterol. 1980;73:503–507
  41. Massicot R, Aubert D, Mboyo A, et al.  Localized esophageal leimyoma and hypertrophic osteoarthropathy. J Pediatr Surg. 1997;32:646–647
  42. Booth BW, Van Nostrand D, Graeber GM. Hypertrophic pulmonary osteoarthropathy and breast cancer. South Med J. 1987;80:383–386
  43. Di Cataldo A, Villari L, Milone P, et al.  Thymic carcinoma, systemic lupus eryrohematosus, and hypertrophic pulmonary osteoarthropaty in an 11-year-old boy (A novel association). Pediatr Hematology and Oncology. 2000;17:701–706
  44. Banerjee AK, Carvalho P. Hypertrophic pulmonary osteoarthropathy due to a pulmonary metastasis from a soft tissue sarcoma. Clin Nucl Med. 1991;16:270–272
  45. Daly PA, Chang P, Goodman L, et al.  Hypertrophic pulmonary osteoarthropathy and metastases from a malignant fibrous histocytoma. Cancer. 1980;45:595–598
  46. Babu KG, Radheshyma , Laltha N, et al.  Hypertropic osteoarthropathy in Hodgkin’s disease. J Assoc Phys Indiana. 1995;43:704–705
  47. Vico P, Delcorde A, Rahier I, et al.  Hypertrophic osteoarthropathy and thyroid cancer. J Rheumatol. 1992;19:1153–1156
  48. Allison NL, Stote RM, Rai R, et al.  Pulmonary osteoarthropathy preceding evidence of metastases from hypernephroma. Lancet. 1981;25:950
  49. Goldstraw P, Walbaum PR. Hypertrophic pulmonary osteoarthropathy and its occurrence of pulmonary metastases from renal cell carcinoma. Thorax. 1976;31:205–211
  50. Ansell BM. Hypertrophic osteoarthropathy in pediatric age. Cln Exp Rheumatol. 1992;10(suppl):15–18
  51. Mill PR, Vallance R, Birnie G, et al.  A prospective survey of radiological bone and joint changes in primary biliary cirrhosis. Clin Radiol. 1981;32:297–302
  52. Simpson EL, Dalinka MK. Association of hypertrophic osteoarthropathy with gastrointestinal polyposis. AJR. 1985;144:983–984
  53. Herneth AM, Breitenseher MJ, Funovics M, et al.  Quiz case 12. Marie-Bamberger syndrome (hypertrophic osteoarthropathy secondary to ulcerative colitis. Eur J Radiol. 1999;32:124–128
  54. O’Neill S, Ryan M, Fieding JF. Hypertrophic pulmonary osteoarthritis and regional enteritis. J Med Sci. 1981;150:385–386
  55. Greenwald M, Coupler R, Laxer R, et al.  Gastro-esophageal reflux and esophagitis-associated hypertrophic osteoarthropathy. J Pediatr Gastroenterol Nutr. 1996;23:178–181
  56. Flavell G. Reversal of pulmonary osteoarthropathy by vagotomy. Lancet. 1956;270:260–262
  57. Yacoub M. Cervical vagotomy for pulmonary osteoarthropathy. Br J Dis Chest. 1965;59:28–31
  58. Major NM, Tehranzadeh J. Musculoskeletal manifestations of AIDS. Radiol Clin North Am. 1997;35:1167–1189
  59. Tas F, Aydiner A, Tenekeci N, et al.  Hypertrophic osteoarthropathy associated with docetaxel treatment. Clin Oncol. 2001;13:145–146
  60. Lofter WS, Walker TM. Hodgkin’s disease and hypertrophic pulmonary osteoarthropathy. Complete clearing following radiotherapy. West Indian Med. 1978;27:227–230
  61. Shapiro LM, Mackinnon J. Resolution of hypertrophic pulmonary osteoarthropathy following treatment of subacute infective endocarditis. Postgrad Med J. 1980;56:513–515
  62. Haslock I, Vasanthakumar V. Disappearing hypertrophic osteoarthropathy. Br J Rehumatol. 1988;27:143–145
  63. Crevenna R, Ouittan M, Hulsmann M, et al.  Hypertrophic osteoarthropathy caused by PGE1 in a patient with heart failure during cardiac rehabilitation. Wein Klin Wochenschr. 2002;114:115–118

PII: S0001-2998(04)00002-9

doi: 10.1053/j.semnuclmed.2004.01.001

Seminars in Nuclear Medicine
Volume 34, Issue 2 , Pages 159-163 , April 2004

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