« Previous
Seminars in Nuclear Medicine
Volume 35, Issue 3
, Pages 202-211
, July 2005
Treatment of Non-Hodgkin’s Lymphoma (NHL) With Radiolabeled Antibodies (mAbs)
References
- . Treatment of non-Hodgkin’s lymphoma . N Engl J Med . 1993;328:1023–1030
- Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin’s lymphoma . N Engl J Med . 1993;328:1002–1006
- Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma (Half of patients respond to a four-dose treatment program) . J Clin Oncol . 1998;16:2825–2833
- CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma . N Engl J Med . 2002;346:235–242
- Randomized controlled trial of yttrium-90-labeled ibritumomab tiuxetan radioimmunotherapy versus rituximab immunotherapy for patients with relapsed refractory low-grade, follicular, or transformed B-cell non-Hodgkin’s lymphoma . J Clin Oncol . 2002;20:2453–2463
- Pivotal study of iodine I 131 tositumomab for chemotherapy-refractory low-grade or transformed low-grade B-cell non-Hodgkin’s lymphomas . J Clin Oncol . 2001;19:3918–3928
- Treatment of non-Hodgkin’s lymphoma with radiolabeled murine, chimeric, or humanized LL2, an anti-CD22 monoclonal antibody . Cancer Res . 1995;55:5899s–5907s
- Pharmacokinetics, dosimetry and initial therapeutic results with 131I- and 111In-/90Y-labeled humanized LL2 anti-CD22 monoclonal antibody (MAb) in patients with relapsed/refractory non-Hodgkin’s lymphoma (NHL) . Clin Cancer Res . 1999;5:3292s–3303s
- Low-dose fractionated radioimmunotherapy for B-cell malignancies using 131I-Lym-1 antibody . Cancer Biother Radiopharm . 1998;13:239–254
- Maximum tolerated dose, toxicity, and efficacy of 131I-Lym-1 antibody for fractionated radioimmunotherapy of non-Hodgkin’s lymphoma . J Clin Oncol . 1998;16:3246–3256
-
.
Radioiodine-labeled compounds previously or currently used for tumor localization
.
Proceedings of an Advisory Group Meeting on Tumor Localization with Radioactive Agents. Panel Proceedings Series
. Vienna, Austria: International Atomic Energy Agency; 1974;
Agency IAE
- Isotopic immunoglobulin in an integrated multimodal treatment program for a primary liver cancer. A case report . Cancer Treat Rep . 1979;63:131–134
- . Continuous culture of fused cells secreting antibody of predefined specificity . Nature . 1975;256:495–497
- Diagnosis of and therapy for solid tumors with radiolabeled antibodies and immune fragments . Cancer Treat Rep . 1984;68:317–328
- Treatment of a patient with B cell lymphoma by I-131 Lym-1 monoclonal antibodies . Int J Biol Markers . 1987;2:49–53
- Serotherapy of a patient with a monoclonal antibody directed against a human lymphoma-associated antigen . Cancer Res . 1980;40:3147–3154
- Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody . N Engl J Med . 1982;306:517–522
-
Pilot studies of radioimmunotherapy of B cell lymphoma and leukemia using I-131 Lym-1 monoclonal antibody
.
Antibody Immunoconj Radiophar
. 1988;1:17–33
-
Fractionated radioimmunotherapy of B-cell malignancies with 131I- Lym-1
.
Cancer Res
. 1990;50(suppl):1014–1016
- Treatment of refractory non-Hodgkin’s lymphoma with radiolabeled MB-1 (anti-CD37) antibody . J Clin Oncol . 1989;7:1027–1038
- . Radioimmunotherapy of the non-Hodgkin’s lymphomas . Semin Radiat Oncol . 1995;5:331–341
-
.
High response rates and durable remissions in patients with previously untreated, advanced-stage, follicular lymphoma treated with tositumomab and iodine I-131 tositumomab (Bexxar)
.
Blood
. 2002;100:356a
- Phase II trial of 131I-B1 (anti-CD20) antibody therapy with autologous stem cell transplantation for relapsed B cell lymphomas . Lancet . 1995;346:336–340
- Phase I/II trial of IDEC-Y2B8 radioimmunotherapy for treatment of relapsed or refractory CD20 B-cell non-Hodgkin’s lymphoma . J Clin Oncol . 1999;17:3793–3803
- Treatment with ibritumomab tiuxetan radioimmunotherapy in patients with rituximab-refractory follicular non-Hodgkin’s lymphoma . J Clin Oncol . 2002;20:3262–3269
- Radiation dosimetry results for Zevalin radioimmunotherapy of rituximab-refractory non-Hodgkin lymphoma . Cancer . 2002;94:1349–1357
-
Radiation exposure is very low to family members of patients treated with yttrium-90 Zevalin TM anti-CD20 monoclonal antibody therapy for lymphoma
.
Eur J Nucl Med
. 2001;28:1198
- Administration guidelines for radioimmunotherapy of non-Hodgkin’s Lymphoma with 90Y-labeled anti-CD20 monoclonal antibody . J Nucl Med . 2002;43:267–272
- . Safety of yttrium-90 ibritumomab tiuxetan radioimmunotherapy for relapsed low-grade, follicular, or transformed non-Hodgkin’s lymphoma . J Clin Oncol . 2003;21:1263–1270
- Phase I/II trial of multiple dose 131Iodine-MAb LL2 (CD22) in patients with recurrent non-Hodgkin’s lymphoma . Leuk Lymphoma . 2000;38:91–101
- Targeting, dosimetry, and radioimmunotherapy of B-cell lymphomas with iodine-131-labeled LL2 monoclonal antibody . J Clin Oncol . 1991;9:548–564
- RIT of non-Hodgkin’s lymphoma with 90Y-DOTA humanized anti-CD22 IgG (90Y-Epratuzumab) (Do tumor targeting and dosimetry predict therapeutic response?) . J Nucl Med . 2003;44:2000–2018
- 90Y-DOTA-hLL2 (An agent for radioimmunotherapy of non-Hodgkin’s lymphoma) . J Nucl Med . 2003;44:77–84
- Radioimmunotherapy using 131I-labeled anti-CD22 monoclonal antibody (LL2) in patients with previously treated B-cell lymphomas . Clin Cancer Res . 1999;5:3287s–3291s
-
Durable response to 90Y-epratuzumab (hLL2) in B-cell lymphoma failing chemotherapy by using dose-fractionation schedule
.
Blood
. 2001;98:2524
-
Final results of a phase I RIT trial using 186Re-Epratuzumab for the treatment of patients with non-Hodgkin’s lymphoma
.
Clin Cancer Res
. 2003;9:3995s–4002s
- . Radioimmunotherapy of B-cell non-Hodgkin’s lymphoma (From clinical trials to clinical practice) . J Nucl Med . 2002;43:1507–1529
-
Toxicities and side effects associated with intravenous infusions of murine monoclonal antibodies
.
J Biol Response Modifiers
. 1986;5:73–84
- Pretargeted radioimmunotherapy (PRIT) for treatment of non-Hodgkin’s lymphoma (NHL) (Initial phase I/II study results) . Cancer Biother Radiopharm . 2000;15:15–29
- 67Cu-versus 131I-labeled Lym-1 antibody (Comparative pharmacokinetics and dosimetry in patients with non-Hodgkin’s lymphoma) . Clin Cancer Res . 1999;5:533–541
- Antilymphoma Effects of Anti-HLA-DR and CD20 monoclonal antibodies (Lym-1 and Rituximab) on human lymphoma cells . Cancer Biother Radiopharm . 2004;19:545–561
- . Immunotherapy of non-Hodgkin’s lymphoma with hLL2 (Epratuzumab, an anti-CD22 monoclonal antibody) and HuID10 (Apolizumab) . Semin Oncol . 2002;29:81–86
- Effect of the extent of chelate substitution on the immunoreactivity and biodistribution of 2IT-BAT-Lym-1 immunoconjugates . Cancer Res . 1995;55:878–884
- Comparative toxicity studies of yttrium-90 MX-DTPA and 2-IT-BAD conjugated monoclonal antibody (BrE-3) . Cancer . 1994;73:1012–1022
-
Preclinical evaluation of cathepsin-degradable peptide linkers for radioimmunoconjugates
.
Clin Cancer Res
. 2003;9(suppl):3865–3872
- Radioimmunotherapy with iodine (131)I tositumomab for relapsed refractory B-cell non-Hodgkin lymphoma (Updated results and long-term follow-up of the University of Michigan experience) . Blood . 2000;96:1259–1266
-
Final dosimetry results of IDEC-Y2B8 phase I/II 90Yttrium radioimmunotherapy trial on non-Hodgkin’s lymphoma (NHL)
.
J Nucl Med
. 1999;40:64P
- Rationales, evidence and design considerations in multiple dose (fractionated) radioimmunotherapy . Cancer . 2002;94:1332–1348
- Maximum tolerated dose of 67Cu-2IT-BAT-Lym-1 for fractionated radioimmunotherapy of non-Hodgkin’s lymphoma (A pilot study) . Anticancer Res . 1998;18:2779–2788
- Dose fractionation of radiolabeled antibodies in patients with metastatic colon cancer . J Nucl Med . 1992;33:1648–1653
-
.
Radioimmunotherapy
.
In:
Haynie TP
editors.
Nuclear Medicine
(Oncology)
. (ed 1). Reston, VA: Society of Nuclear Medicine; 2000;p. 39–74
-
Radiometals as payloads for radioimmunotherapy for lymphoma
.
Clinical Lymphoma
. 2004;5(suppl):5–10
- Radioimmunotherapy of human B-cell lymphoma with Y-90-conjugated antiidiotype monoclonal antibody . Cancer Res . 1990;50(suppl):1022s–1028s
PII: S0001-2998(05)00016-4
doi: 10.1053/j.semnuclmed.2005.02.006
© 2005 Elsevier Inc. All rights reserved.
« Previous
Seminars in Nuclear Medicine
Volume 35, Issue 3
, Pages 202-211
, July 2005
