Seminars in Nuclear Medicine
Volume 35, Issue 4 , Pages 257-265, October 2005

Changing Concepts in the Management of Differentiated Thyroid Cancer

  • Charles M. Intenzo, MD

      Affiliations

    • Division of Nuclear Medicine, Department of Radiology, Thomas Jefferson University, Philadelphia, PA.
    • Corresponding Author InformationAddress reprint requests to Charles M. Intenzo, MD, Division of Nuclear Medicine, Department of Radiology, Thomas Jefferson University, 132 S. 10th Street, Room 861, Philadelphia, PA 19107.
    • ,
  • Serge Jabbour, MD

      Affiliations

    • Division of Endocrinology and Metabolism, Department of Medicine, Thomas Jefferson University, Philadelphia, PA.
    • ,
  • Hung Q. Dam, MD

      Affiliations

    • Division of Nuclear Medicine, Department of Medicine, Christiana Hospital, Wilmington, DE.
    • ,
  • David M. Capuzzi, MD, PhD

      Affiliations

    • Division of Endocrinology and Metabolism, Department of Medicine, Thomas Jefferson University, Philadelphia, PA.

The management of patients with differentiated thyroid cancer has changed significantly over the last few decades. Mortality has decreased as the result of earlier detection, refined surgical approaches, subsequent radioiodine ablation, and the development of more sensitive methods for detecting and monitoring disease recurrence. The latter has been facilitated by serum thyroglobulin measurements, the use of recombinant human thyrotropin, and the use of 18F-deoxyglucose/positron emission tomography in selected instances where radioiodine imaging fails to locate known or suspected recurrent or metastatic disease.

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PII: S0001-2998(05)00030-9

doi:10.1053/j.semnuclmed.2005.05.003

Seminars in Nuclear Medicine
Volume 35, Issue 4 , Pages 257-265, October 2005

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