Seminars in Nuclear Medicine
Volume 36, Issue 4 , Pages 286-294 , October 2006

The Role of Single-Photon Emission Computed Tomography/Computed Tomography in Benign and Malignant Bone Disease

  • Marius Horger, MD

      Affiliations

    • Department of Diagnostic Radiology, Eberhard-Karls, University, Tübingen, Germany.
    • Corresponding Author InformationAddress reprint requests to Marius Horger, MD, Department of Diagnostic Radiology, Eberhard-Karls-Universität, Hoppe-Seyler-Str 3, 72076 Tübingen, Germany.
    • ,
  • Roland Bares, MD

      Affiliations

    • Department of Nuclear Medicine, Eberhard-Karls-University, Tübingen, Germany.

References 

  1. Wahl RL , Quint LE , Cieslk RD , et al.   “Anatometabolic” tumor imaging (Fusion of FDG-PET with CT or MRI to localize foci of increased activity) . J Nucl Med . 1993;34:1190–1197
  2. Shreve PD . Adding structure to function . J Nucl Med . 2000;41:1380–1382 (invited commentary)
  3. Eubank WB , Markoff DA , Schmiedl UT , et al.   Imaging of oncologic patients: benefit of combined CT and FDG-PET in the diagnosis of malignancy . AJR Am J Roentgenol . 1998;1103–1110
  4. Even-Sapir E , Keidar Z , Sachs J , et al.   The new technology of combined transmission and emission tomography in evaluation of endocrine neoplasms . J Nucl Med . 2001;42:998–1004
  5. Front D , Israel O , Jerushalmi J , et al.   Quantitative bone scintigraphy using SPECT . J Nucl Med . 1989;30:240–245
  6. Georgi P , Kaps HP , Sinn HJ . Leukozytenszintigraphie bei entzündlichen Prozessen der Wirbelsäule . Radiologe . 1985;25:324–328
  7. Palestro C , Kipper S , Weiland F , et al.   Osteomyelitis: Diagnosis with 99mTc-labelled antigranulocyte antibodies compared with diagnosis with 111In-labelled leukocytes-Initial experience . Radiology . 2002;223:758–764
  8. Clain A . Secondary malignant disease of bone . Br J Cancer . 1965;19:15–29
  9. Pomeranz SJ , Pretorius HT , Ramsingh PS . Bone scintigraphy and multimodality imaging in bone neoplasia: strategies for imaging in the new health climate . Semin Nucl Med . 1994;24:188–207
  10. Krishnamurthy GT , Tubis M , Hiss J , et al.   Distribution pattern of metastatic bone disease (A need for total body skeletal image) . JAMA . 1977;237:2504–2506
  11. McNeil BJ . Value of bone scanning in neoplastic disease . Semin Nucl Med . 1984;14:277–286
  12. Abrams HL , Spiro R , Goldstein N . Metastases in carcinoma (Analysis of 1000 autopsied cases) . Cancer . 1950;2:74–85
  13. Han BK , Ryu J , Moon DH , et al.   Bone SPECT imaging of vertebral hemangioma (Correlation with MR imaging and symptoms) . Cli Nucl Med . 1995;20:916–921
  14. Bamberger DM . Diagnosis and treatment of osteomyelitis . Comp Ther . 1990;16:48–53
  15. Becker W , Goldenberg DM , Wolf F . The use of monoclonal antibodies and antibody fragments in the imaging of infectious lesions . Semin Nucl Med . 1994;24:142–153
  16. Reuland P , Winkler KH , Heuchert T , et al.   Detection of infection in postoperative patients with technetium-99m-labelled monoclonal antibodies against granulocytes . J Nucl Med . 1991;32:2209–2214
  17. Kaim A , Maurer T , Ochsner P , et al.   Chronic complicated osteomyelitis of the appendicular skeleton: diagnosis with technetium-99m labelled monoclonal antigranulocyte antibody-immunoscintigraphy . Eur J Nucl Med . 1997;24:732–738
  18. Palestro CJ , Chun CK , Swyer AJ , et al.   Radionuclide diagnosis of vertebral osteomyelitis: indium-111 leucocyte and technetium-99m methylene diphosphonate bone scintigraphy . J Nucl Med . 1990;31:413–416
  19. Palestro CJ , Kipper S , Weiland F , et al.   Osteomyelitis: Diagnosis with 99m-Tc-labelled antigranulocyte antibodies compared with diagnosis with 111 In-labelled leukocytes-Initial experience . Radiology . 2002;223:758–764
  20. Maurer AH , Chen DCP , Camargo EE , et al.   Utility of three-phase scintigraphy in suspected osteomyelitis . J Nucl Med . 1981;22:941–949
  21. Israel O , Gips S , Jerushalmi J , et al.   Osteomyelitis and soft tissue infection: differential diagnosis with 24 hour/4hour ratio of Tc99m MDP uptake . Radiology . 1987;163:725–726
  22. Wing VW , Jeffrey RB , Federle MP , et al.   Chronic osteomyelitis examined by CT . Radiology . 1985;154:171–174
  23. Seltzer SE . Value of computed tomography in planning medical and surgical treatment of chronic osteomyelitis . J Comput Assist Tomogr . 1984;8:482–487
  24. Tumeh SS , Aliabadi P , Weissman BN , et al.   Disease activity in osteomyelitis: role of radiography . Radiology . 1987;165:781–784
  25. Crim JR , Seeger LL . Imaging evaluation of osteomyelitis . Crit Rev Diagn Imaging . 1994;35:201–256
  26. Love C , Din AS , Tomas MB , et al.   Radionuclide bone imaging: an illustrative review . Radiographics . 2003;23:341–358

PII: S0001-2998(06)00021-3

doi: 10.1053/j.semnuclmed.2006.05.001

Seminars in Nuclear Medicine
Volume 36, Issue 4 , Pages 286-294 , October 2006

Article Tools

* Image Usage & Resolution