Seminars in Nuclear Medicine
Volume 38, Issue 2 , Pages 141-148 , March 2008

Positron Emission Tomography/Computed Tomography for Target Delineation in Head and Neck Cancers

  • Peter H. Ahn, MD

      Affiliations

    • Corresponding Author InformationAddress reprint requests to Peter H. Ahn, Department of Radiation Oncology, Department of Radiation Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, 111 East 210 Street, Bronx, NY 10467.
    • ,
  • Madhur K. Garg, MD

References 

  1. Chao KS, Deasy JO, Markman J, et al. A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: Initial results. Int J Radiat Oncol Biol Phys. 2001;49:907–916
  2. Eisbruch A, Haken RKT, Kim HM, et al. Dose, volume, and function relationships in parotid salivary glands following conformal and intensity-modulated irradiation of head-and-neck cancer. Int J Radiat Oncol Biol Phys. 1999;45:577–587
  3. Tsien C, Eisbruch A, McShan D, et al. Intensity-modulated radiation therapy (IMRT) for locally advanced paranasal sinus tumors: Incorporating clinical decisions in the optimization process. Int J Radiat Oncol Biol Phys. 2003;55:776–784
  4. Eisbruch A, Schwartz M, Rasch C, et al. Dysphagia and aspiration after chemoradiotherapy for head-and-neck cancer: Which anatomic structures are affected and can they be spared by IMRT?. Int J Radiat Oncol Biol Phys. 2004;60:1425–1439
  5. Al-Sarraf M, LeBlanc M, Giri PG, et al. Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: Phase III Randomized Intergroup Study 0099. J Clin Oncol. 1998;16:1310–1317
  6. Emami B, Lyman J, Brown A, et al. Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys. 1991;21:109–122
  7. Conti PS, Liliean DL, Hawley K, et al. PET and [18F]-FDG in oncology: A clinical update. Nuc Med & Biol. 1996;23:717–735
  8. Di Martino E, Nowak B, Hassan HA, et al. Diagnosis and staging of head and neck cancer: A comparison of modern imaging modalities (positron emission tomography, computed tomography, color-coded duplex sonography) with panendoscopic and histopathologic findings. Arch Otolaryngol Head Neck Surg:. 2000;126:1457–1461
  9. Johansen J, Eigtved A, Buchwald C, et al. Implication of 18F-Fluoro-2-Deoxy-D-glucose positron emission tomography on management of carcinoma of unknown primary in the head and neck: A Danish cohort study. Laryngoscope. 2002;112:2009–2014
  10. Schöder H, Yeung HW, Gonen M, et al. Head and neck cancer: Clinical usefulness and accuracy of PET/CT image fusion. Radiology. 2004;231:65–72
  11. Goerres GW, Gustav K, Steinert HC. Why most PET of lung and head-and-neck cancer will be PET/CT. J Nucl Med. 2004;45:66S–71S
  12. Schwartz DL, Ford E, Rajendran J, et al. FDG-PET/CT imaging for preradiotherapy staging of head-and-neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 2005;61:129–136
  13. Daisne JF, Duprez T, Weynard B, et al. Tumor volume in pharyngolaryngeal squamous cell carcinoma: comparison at CT, MR Imaging, and FDG PET and validation with surgical specimen. Radiology. 2004;233:93–100
  14. Nishioka T, Shiga T, Shirato H, et al. Image fusion between 18FDG-PET and MRI/CT for radiotherapy planning of oropharyngeal and nasopharyngeal carcinomas. Int J Radiat Oncol Biol Phys. 2002;53:1051–1057
  15. Ciernik IF, Dizendorf E, Baumert BG, et al. Radiation treatment planning with an integrated positron emission and computer tomography (PET/CT): A feasibility study. Int J Radiat Oncol Biol Phys. 2003;57:853–863
  16. Heron DE, Andrade RS, Flickinger J, et al. Hybrid PET-CT simulation for radiation treatment planning in head-and-neck cancers: A brief technical report. Int J Radiat Oncol Biol Phys. 2004;60:1419–1424
  17. Paulino AC, Koshy M, Howell R, et al. Comparison of CT- and FDG-PET-defined gross tumor volume in intensity-modulated radiotherapy for head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2005;61:1385–1392
  18. Riegel AC, Berson AM, Destian S, et al. Variability of gross tumor volume delineation in head-and-neck cancer using CT and PET/CT fusion. Int J Radiat Oncol Biol Phys. 2006;65:726–732
  19. El-Bassiouni M, Ciernik IF, Davis JB, et al. [18FDG] PET-CT-based intensity-modulated radiotherapy treatment planning of head and neck cancer. Int J Radiat Oncol Biol Phys. 2007;69:286–293
  20. Wang D, Schultz CJ, Jursinic PA, et al. Initial experience of FDG-PET/CT guided IMRT of head-and-neck carcinoma. Int J Radiat Oncol Biol Phys. 2006;65:143–151
  21. Ahn PH, Mehta K, Mutyala S, et al. PET-CT For Target Delineation for Definitive Radiotherapy in Head and Neck Cancers: The Montefiore/Albert Einstein Experience. 2007;Presented at 2007 ACNP Meeting, San Antonio, TX, Feb
  22. Ashamalla H, Guirgius A, Bieniek E, et al. The impact of positron emission tomography/computed tomography in edge delineation of gross tumor volume for head and neck cancers. Int J Radiat Oncol Biol Phys. 2007;68:388–395
  23. Rajendran JG, Hendrickson KR, Spence AM, et al. Hypoxia imaging-directed radiation treatment planning. Eur J Nucl Med Mol Imaging. 2006;33:S44–S53
  24. Overgaard J, Hansen HS, Overgaard M, et al. A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma (Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85). Radiother Oncol. 1998;46:135–146
  25. Serganova I, Blasberg R. Reporter gene imaging: potential impact on therapy. Nuc Med Biol. 2005;32:763–780
  26. Grosu A, Souvatzoglou M, Roper B, et al. Hypoxia imaging with FAZA-PET and theoretical considerations with regard to dose painting for individualization of radiotherapy in patients with head and neck cancer. Int J Radiat Oncol Biol Phys. 2007;69:541–551
  27. Juweid ME, Cheson BD. Positron-emission tomography and assessment of cancer therapy. N Engl J Med. 2006;354:496–507
  28. Andrade R, Heron R, Degirmenci B, et al. Posttreatment assessment of response using FDG-PET/CT for patients treated with definitive radiation therapy for head and neck cancers. Int J Radiat Oncol Biol Phys. 2006;65:1315–1322
  29. Yao M, Graham M, Hoffman H, et al. The role of post-radiation therapy FDG PET in prediction of necessity for post-radiation therapy neck dissection in locally advanced head-and-neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 2004;59:1001–1010

PII: S0001-2998(07)00140-7

doi: 10.1053/j.semnuclmed.2007.11.002

Seminars in Nuclear Medicine
Volume 38, Issue 2 , Pages 141-148 , March 2008

Article Tools

* Image Usage & Resolution