« Previous
Next »
Seminars in Nuclear Medicine
Volume 39, Issue 6
, Pages 396-407
, November 2009
Prostate Cancer: Role of SPECT and PET in Imaging Bone Metastases
References
- . Skeletal complications of malignancy. Cancer. 1997;80(suppl 8):1588–1594
- . Pathophysiology of bone metastases. Cancer Biol Ther. 2006;5:1078–1081
- Cancer statistics, 2007. CA Cancer J Clin. 2007;57:43–66
- . Prostate Cancer: Can We Reduce Mortality While Preserving the Quality of Life? (vol 1). Washington, DC: US Department of Health and Human Services; 1995;
- . Should mass screening for prostate cancer be introduced at the national level?. WHO Regional Office for Europe's Health Evidence Network Report (HEN); 2004;
- Cancer statistics, 2005. CA Cancer J Clin. 2005;55:10–30
- The impact of the inclusion of endorectal coil magnetic resonance imaging in a multivariate analysis to predict clinically unsuspected extraprostatic cancer. Cancer. 1995;75:2368–2372
- . Radiologic diagnosis of bone metastases. Cancer. 1997;80(suppl 8):1595–1607
- Diagnostic bone scanning in oncology. Semin Nucl Med. 1997;27:107–141
- Comparison of bone single-photon emission tomography and planar imaging in the detection of vertebral metastases in patients with back pain. Eur J Nucl Med. 1998;25:635–638
- Does bone SPECT actually have lower sensitivity for detecting vertebral metastasis than MRI?. J Nucl Med. 1996;37:975–978
- The role of bone SPET study in diagnosis of single vertebral metastases. Anticancer Res. 2000;20:1115–1120
- The central role of osteoblasts in the metastasis of prostate cancer. Cancer Metastasis Rev. 2006;25:601–609
- . Preferential adhesion of prostate cancer cells to a human bone marrow endothelial cell line. J Natl Cancer Inst. 1998;90:118–123
- Interactions of human prostatic epithelial cells with bone marrow endothelium: Binding and invasion. Br J Cancer. 2001;84:1417–1423
- Prostate-specific antigen induces apoptosis of osteoclast precursors: Potential role in osteoblastic bone metastases of prostate cancer. Prostate. 2006;66:1573–1584
- . Bone imaging in prostate cancer. Nat Clin Pract Urol. 2008;5:434–444
- Bone scintigraphy and the added value of SPECT (single photon emission tomography) in detecting skeletal lesions. Q J Nucl Med. 2001;45:27–37
- Preoperative staging of pelvic lymph nodes in prostate cancer by 11C-choline PET. J Nucl Med. 2003;44:331–335
- . Bone scanning in metastatic disease. In: Collier BD editors. Skeletal Nuclear Medicine. St Louis, MO: Mosby; 1996;p. 87–123
- . Skeletal scanning in neoplastic disease. Cancer. 1976;37(suppl 1):480–486
- Metastases seen on SPECT imaging despite a normal planar bone scan. Clin Nucl Med. 1995;20:1052–1054
- Reply. Eur J Nucl Med Mol Imaging. Oct. 23, 2004;
- Skeletal affinity of Tc(V)-DMS is bone cell mediated and pH dependent. Eur J Nucl Med Mol Imaging. 2004;31:388–398
- Prognostic significance of extent of disease in bone in patients with androgen-independent prostate cancer. J Clin Oncol. 1999;17:948–957
- Percentage of the positive area of bone metastasis is an independent predictor of disease death in advanced prostate cancer. Br J Cancer. 2003;88:195–201
- Prognostic value of bone scan in patients with metastatic prostate cancer treated initially with androgen deprivation therapy. J Urol. 2002;168:1423–1426
- . Do bone scans predict prognosis in prostatic cancer? (A report of the EORTC protocol 30762). Br J Urol. 1984;56:58–63
- Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer. JAMA. 1998;280:969–974
- A preoperative nomogram for disease recurrence following radical prostatectomy for prostate cancer. J Natl Cancer Inst. 1998;90:766–771
- The use of prostate-specific antigen in staging patients with newly diagnosed prostate cancer. JAMA. 1993;269:57–60
- PET and prostate cancer. World J Urol. 2004;22:351–352
- Predicting radionuclide bone scan findings in patients with newly diagnosed, untreated prostate cancer: Prostate specific antigen is superior to all other clinical parameters. J Urol. 1991;145:313–318
- . Using prostate-specific antigen to eliminate the staging radionuclide bone scan. Urol Clin North Am. 1997;24:389–394
- Limited role of radionuclide bone scintigraphy in patients with prostate specific antigen elevations after radical prostatectomy. J Urol. 1998;160:1387–1391
- Limited value of bone scintigraphy and computed tomography in assessing biochemical failure after radical prostatectomy. Urology. 2003;61:607–611
- Pattern of prostate-specific antigen (PSA) failure dictates the probability of a positive bone scan in patients with an increasing PSA after radical prostatectomy. J Clin Oncol. 2005;23:1962–1968
- . The role of nuclear medicine in monitoring treatment in skeletal malignancy. Semin Nucl Med. 2001;31:206–211
- Bone metabolic markers in the evaluation of bone scan flare phenomenon in bone metastases of breast cancer. Clin Nucl Med. 1999;24:15–20
- A new parameter for measuring metastatic bone involvement by prostate cancer: The Bone Scan Index. Clin Cancer Res. 1998;4:1765–1772
- . Quantitative evaluation of bone metastases in patients with advanced prostate cancer during systemic treatment. BJU Int. 2003;92:379–383discussion 383-374
- Role of SPECT in differentiating malignant from benign lesions in the lower thoracic and lumbar vertebrae. Radiology. 1993;187:193–198
- . SPECT bone scanning of the spine. Semin Nucl Med. 1998;28:78–94
- . Bone scanning in clinical oncology: Does it have a future?. Eur J Nucl Med. 1998;25:1219–1223
- Comparison of FDG PET and SPECT for detection of bone metastases in breast cancer. Am J Roentgenol. 2005;184:1266–1273
- The detection of bone metastases in patients with high-risk prostate cancer: 99mTc-MDP planar bone scintigraphy, single- and multi-field-of-view SPECT, 18F-fluoride PET, and 18F-fluoride PET/CT. J Nucl Med. 2006;47:287–297
- Fast modelling of the collimator-detector response in Monte Carlo simulation of SPECT imaging using the angular response function. Phys Med Biol. 2005;50:1791–1804
- Phase I trial of 177lutetium-labeled J591, a monoclonal antibody to prostate-specific membrane antigen, in patients with androgen-independent prostate cancer. J Clin Oncol. 2005;23:4591–4601
- Phase I trial of the prostate-specific membrane antigen-directed immunoconjugate MLN2704 in patients with progressive metastatic castration-resistant prostate cancer. J Clin Oncol. 2008;26:2147–2154
- Phase I trial of yttrium-90-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 for androgen-independent prostate cancer. J Clin Oncol. 2004;22:2522–2531
- Pilot trial of unlabeled and indium-111-labeled anti-prostate-specific membrane antigen antibody J591 for castrate metastatic prostate cancer. Clin Cancer Res. 2005;11:7454–7461
- . Location of prostate-specific membrane antigen in the LNCaP prostate carcinoma cell line. Prostate. 1997;30:232–242
- Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature. Cancer Res. 1999;59:3192–3198
- . Phase I clinical trial targeting a monoclonal antibody (mAb) to the extracellular domain of prostate specific membrane antigen (PSMAext) in hormone-independent patients. J Urol. 2000;163(suppl 4):160–167
- Progress in SPECT/CT imaging of prostate cancer. Technol Cancer Res Treat. 2006;5:329–336
- Prostate-specific membrane antigen expression in normal and malignant human tissues. Clin Cancer Res. 1997;3:81–85
- Prostate-specific membrane antigen expression is greatest in prostate adenocarcinoma and lymph node metastases. Urology. 1998;52:637–640
- Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy. Urology. 1996;48:326–334
- Radioimmunoscintigraphy of pelvic lymph nodes with 111indium-labeled monoclonal antibody CYT-356. J Urol. 1994;152:1952–1955
- . Monoclonal antibody imaging of occult prostate cancer in patients with elevated prostate-specific antigen (Positron emission tomography and biopsy correlation). Clin Nucl Med. 1996;21:704–713
- Multicenter radioimmunoscintigraphic evaluation of patients with prostate carcinoma using indium-111 capromab pendetide. Cancer. 1998;83:739–747
- Comparison of clinical staging algorithms and 111indium-capromab pendetide immunoscintigraphy in the prediction of lymph node involvement in high risk prostate carcinoma patients. Cancer. 1999;85:1586–1592
- . The role of monoclonal antibody in the management of prostate adenocarcinoma. J Urol. 1998;160:2393–2395
- . Novel tracers and their development for the imaging of metastatic prostate cancer. J Nucl Med. 2008;49:2031–2041
- . The role of positron emission tomography in the management of bone metastases. Cancer. 2000;88(suppl 12):2927–2933
- Cost-effectiveness of PET imaging in clinical oncology. Nucl Med Biol. 1996;23:737–743
- Analytical decision model for the cost-effective management of solitary pulmonary nodules. J Clin Oncol. 1998;16:2113–2125
- FDG-PET: Procedure guidelines for tumour imaging. Eur J Nucl Med Mol Imaging. 2003;30:BP115–BP124
- . On the origin of cancer cells. Science. 1956;123:309–314
- . Influence of hypoxia on tracer accumulation in squamous-cell carcinoma: In vitro evaluation for PET imaging. Nucl Med Biol. 1996;23:941–946
- Regulation of prostate cancer cell division by glucose. J Cell Physiol. 1999;180:431–438
- Novo synthesis of diacylglycerol from glucose (A new pathway of signal transduction in human neutrophils stimulated during phagocytosis of beta-glucan particles). J Biol Chem. 1991;266:8034–8038
- Metabolic imaging of untreated prostate cancer by positron emission tomography with 18fluorine-labeled deoxyglucose. J Urol. 1996;155:994–998
- Metastatic prostate cancer: Initial findings of PET with 2-deoxy-2-[F-18]fluoro-d-glucose. Radiology. 1996;199:751–756
- Detection of bony metastases of androgen-independent prostate cancer by PET-FDG. Nucl Med Biol. 1996;23:693–697
- Detection of bone metastases in breast cancer by 18FDG PET: Differing metabolic activity in osteoblastic and osteolytic lesions. J Clin Oncol. 1998;16:3375–3379
- Positron emission tomography of a human prostate cancer xenograft: Association of changes in deoxyglucose accumulation with other measures of outcome following androgen withdrawal. Cancer Res. 1998;58:3009–3014
- Comparison of helical computerized tomography, positron emission tomography and monoclonal antibody scans for evaluation of lymph node metastases in patients with prostate specific antigen relapse after treatment for localized prostate cancer. J Urol. 1999;162:1322–1328
- 11C-acetate PET imaging of prostate cancer. J Nucl Med. 2002;43:181–186
- Whole-body bone marrow MRI in patients with metastatic disease to the skeletal system. J Comput Assist Tomogr. 1999;23:123–129
- Reliability of symptoms to determine use of bone scans to identify bone metastases in lung cancer: Prospective study. BMJ. 2004;328:1051–1052
- Omission of bone scanning according to staging guidelines leads to futile therapy in non-small cell lung cancer. Eur J Nucl Med Mol Imaging. 2004;31:964–968
- . The role of fluorodeoxyglucose, 18F-dihydroxyphenylalanine, 18F-choline, and 18F-fluoride in bone imaging with emphasis on prostate and breast. Semin Nucl Med. 2006;36:73–92
- Fluorinated deoxyglucose positron emission tomography imaging in progressive metastatic prostate cancer. Urology. 2002;59:913–918
- . Citrate metabolism of normal and malignant prostate epithelial cells. Urology. 1997;50:3–12
- Characterization of acetate metabolism in tumor cells in relation to cell proliferation: Acetate metabolism in tumor cells. Nucl Med Biol. 2001;28:117–122
- . Imaging of the pancreas and related diseases with PET carbon-11-acetate. J Nucl Med. 1997;38:1305–1310
- Carbon-11-acetate PET imaging in renal disease. J Nucl Med. 1995;36:1595–1601
- 11C-acetate PET imaging of prostate cancer: Detection of recurrent disease at PSA relapse. J Nucl Med. 2003;44:549–555
- Carbon-11 acetate positron emission tomography can detect local recurrence of prostate cancer. Eur J Nucl Med Mol Imaging. 2002;29:1380–1384
- (11)C-acetate PET in the early evaluation of prostate cancer recurrence. Eur J Nucl Med Mol Imaging. 2007;34:185–196
- 18F-fluoroacetate: A potential acetate analog for prostate tumor imaging—In vivo evaluation of 18F-fluoroacetate versus 11C-acetate. J Nucl Med. 2007;48:420–428
- Imaging of prostate cancer metastases with 18F-fluoroacetate using PET/CT. Eur J Nucl Med Mol Imaging. 2004;31:797
- [(18)F]fluorocholine PET/CT imaging for the detection of recurrent prostate cancer at PSA relapse: Experience in 100 consecutive patients. Eur J Nucl Med Mol Imaging. 2006;33:1387–1398
- Localization of primary prostate cancer with dual-phase 18F-fluorocholine PET. J Nucl Med. 2006;47:262–269
- Imaging prostate cancer with 11C-choline PET/CT. J Nucl Med. 2006;47:1249–1254
- Imaging of brain tumor with [methyl-11C]choline. J Nucl Med. 1997;38:842–847
- . Imaging of prostate cancer using carbon-11-choline. J Nucl Med. 1998;39:990–995
- Sensitive detection of mediastinal lymph node metastasis of lung cancer with 11C-choline PET. J Nucl Med. 2000;41:1507–1513
- Positron emission tomography of esophageal carcinoma using (11)C-choline and (18)F-fluorodeoxyglucose: A novel method of preoperative lymph node staging. Cancer. 1999;86:1638–1648
- In vivo uptake of [11C]choline does not correlate with cell proliferation in human prostate cancer. Eur J Nucl Med Mol Imaging. 2005;32:668–673
- [11C]choline as a PET biomarker for assessment of prostate cancer tumor models. Bioorg Med Chem. 2004;12:2887–2893
- . Development of (18)F-fluoroethylcholine for cancer imaging with PET: Synthesis, biochemistry, and prostate cancer imaging. J Nucl Med. 2002;43:187–199
- Synthesis and evaluation of 18F-labeled choline as an oncologic tracer for positron emission tomography: Initial findings in prostate cancer. Cancer Res. 2001;61:110–117
- Synthesis and evaluation of (18)F-labeled choline analogs as oncologic PET tracers. J Nucl Med. 2001;42:1805–1814
- Pharmacokinetics and radiation dosimetry of 18F-fluorocholine. J Nucl Med. 2002;43:92–96
- Evaluation of lymph node and bone metastases with fluor choline (FCH) PET—CT in the follow up of prostate cancer patients. Eur J Nucl Med Mol Imaging. 2006;33(suppl 2):208–209
- Fluor choline (FCH) PET—CT in preoperative staging of prostate cancer. Eur J Nucl Med Mol Imaging. 2006;33(suppl 2):207–208
- . [18F]fluorocholine PET/CT in the assessment of bone metastases in prostate cancer. Eur J Nucl Med Mol Imaging. 2007;34:1316–1317author reply 1318-1319
- Fluorocholine PET/CT in patients with prostate cancer: Initial experience. Radiology. 2005;235:623–628
- Evaluation of [(18)F]-choline PET/CT for staging and restaging of prostate cancer. Eur J Nucl Med Mol Imaging. 2008;35:253–263
- The use of F-18 choline PET in the assessment of bone metastases in prostate cancer: Correlation with morphological changes on CT. Mol Imaging Biol. 2009;[Epub ahead of print]
- Fluor choline (FCH) PET—CT in preoperative staging and follow up of prostate cancer. Mol Imaging Biol. 2006;8:69
- Assessment of bone metastases in patients with prostate cancer by dual—phase F–18 fluor choline PET/CT. Eur J Nucl Med Mol Imaging. 2006;33(Suppl 2):208
- . [18F]fluorocholine PET/CT in the assessment of bone metastases in prostate cancer. Eur J Nucl Med Mol Imaging. 2007;34:1316–1317
- . Fluorine-18: A new isotope for bone scanning. J Nucl Med. 1962;3:332–334
- Sensitivity in detecting osseous lesions depends on anatomic localization: Planar bone scintigraphy versus 18F PET. J Nucl Med. 1999;40:1623–1629
- Positron emission tomography and bone metastases. Semin Nucl Med. 2005;35:135–142
- Skeletal metastases from breast cancer: Uptake of 18F-fluoride measured with positron emission tomography in correlation with CT. Skeletal Radiol. 1998;27:72–76
- Evaluation of the skeletal kinetics of fluorine-18-fluoride ion with PET. J Nucl Med. 1992;33:633–642
- Early detection and accurate description of extent of metastatic bone disease in breast cancer with fluoride ion and positron emission tomography. J Clin Oncol. 1999;17:2381–2389
- Detection of bone metastases in patients with prostate cancer by 18F fluorocholine and 18F fluoride PET-CT: A comparative study. Eur J Nucl Med Mol Imaging. 2008;35:1766–1774
- . Implications of PET based molecular imaging on the current and future practice of medicine. Semin Nucl Med. 2004;34:56–69
- . Increased amounts of D-enantiomer dependent on alkaline concentration in the synthesis of L-[methyl-11C]methionine. Int J Rad Appl Instrum [A]. 1988;39:311–314
- Imaging of non-small-cell lung carcinoma with carbon-11-methionine: Relationship between radioactivity uptake and flow-cytometric parameters. J Nucl Med. 1993;34:1886–1891
- Combined 18F-FDG and 11C-methionine PET scans in patients with newly progressive metastatic prostate cancer. J Nucl Med. 2002;43:46–55
- Detection of prostate cancer with 11C-methionine positron emission tomography. J Urol. 2005;173:66–69discussion 69
- Preclinical evaluation of fluorine-18-labeled androgen receptor ligands in baboons. J Nucl Med. 1996;37:1009–1015
- . Biology of progressive, castration-resistant prostate cancer: Directed therapies targeting the androgen-receptor signaling axis. J Clin Oncol. 2005;23:8253–8261
- Tumor localization of 16beta-18F-fluoro5alpha-dihydrotestosterone versus 18F-FDG in patients with progressive, metastatic prostate cancer. J Nucl Med. 2004;45:366–373
- Positron tomographic assessment of androgen receptors in prostatic carcinoma. Eur J Nucl Med Mol Imaging. 2005;32:344–350
- MicroPET imaging of a gastrin-releasing peptide receptor-positive tumor in a mouse model of human prostate cancer using a 64Cu-labeled bombesin analogue. Bioconjug Chem. 2003;14:756–763
- MicroPET and autoradiographic imaging of GRP receptor expression with 64Cu-dota-[Lys3]bombesin in human prostate adenocarcinoma xenografts. J Nucl Med. 2004;45:1390–1397
- GRP receptor-targeted PET of a rat pancreas carcinoma xenograft in nude mice with a 68Ga-labeled bombesin(6-14) analog. J Nucl Med. 2005;46:691–699
- 18F-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer. J Nucl Med. 2006;47:492–501
- Initial experience with the radiotracer anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid with PET/CT in prostate carcinoma. J Nucl Med. 2007;48:56–63
PII: S0001-2998(09)00042-7
doi: 10.1053/j.semnuclmed.2009.05.003
© 2009 Elsevier Inc. All rights reserved.
« Previous
Next »
Seminars in Nuclear Medicine
Volume 39, Issue 6
, Pages 396-407
, November 2009
